Sm-a-actin
WebbSM a-actin, SM myosin heavy chain (MHC), and h1 calponin. However, induction of SM a-actin by TGF-bis not restricted to SMCs. A study by Shah et al4 demonstrated that TGF-b stimulated differentiation of neural crest cells into SMCs or SMC-like cells based on morphological criteria and the induction of SM a-actin and h1 calponin. Of particular Webbα-Smooth Muscle Actin Antibody. #14968. 使用 α-Smooth Muscle Actin Antibody （上）与 GAPDH (D16H11) XP ® Rabbit mAb #5174 （下）对多个组织的提取物进行蛋白质 …
Sm-a-actin
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ACTA2 (commonly referred to as alpha-smooth muscle actin or α-SMA) is often used as a marker of myofibroblast formation. Studies have shown that ACTA2 is associated with TGF-β pathway that enhances contractile properties of hepatic stellate cells leading to liver fibrosis and cirrhosis . Visa mer ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a Visa mer • Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639. S2CID Visa mer • GeneReviews/NIH/NCBI/UW entry on Thoracic Aortic Aneurysms and Aortic Dissections • Human ACTA2 genome location and ACTA2 gene details page in the Visa mer WebbSmooth muscle alpha-actin (αSMA) is the definitive marker for the activated cardiac fibroblast population known as the myofibroblast (Frangogiannis et al., 2000), but this …
WebbThe smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is … WebbStress may directly activate transcription of the α-SM actin gene, since application of force across integrin binding sites has been shown to up-regulate α-SM actin promoter activity. 52 As mentioned above, mechanical force alone is not generally sufficient to induce myofibroblast differentiation and other factors are needed to act in concert, specifically …
Webb30 maj 2024 · Western blot results showed that the expression of SM-a-actin and SM-22a was increased, whereas the expression of MMP-2 and TNF-α was decreased in VSMCs treated with 3-MA, in relative to shear stress group (Fig. 4), suggesting that the induction of autophagy could partially block the phenotypic transition of VSMCs. WebbAlpha smooth muscle actin antibody (ab5694) stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also …
Webbα-smooth muscle actin, a smooth muscle cell-specific protein, is also known as aortic smooth muscle or a smooth muscle actin (α-SMA, SMactin, α-SM-actin, ASMA). It belongs to the actin family.It is predominantly found in cells of the smooth muscle lineages. It has been reported that α-smooth muscle actin was also found in certain non-muscle ...
Webb22 okt. 2024 · Vascular smooth muscle cells (VSMCs) are indispensable components in foam cell formation in atherosclerosis. However, the mechanism behind foam cell formation of VSMCs has not been addressed. We ... imdb scum of the earthWebb1 mars 2003 · We hypothesized that ablation of smooth muscle α-actin (SM α-A), a contractile-cytoskeletal protein expressed in airway smooth muscle (ASM) cells, … imdb the breakupWebbSmooth Muscle Actin ( Figures 25-3, A, and 25-4, A) The smooth muscle actin (SMA) marker has a relatively long track record of use as a myoepithelial marker in breast … dutch emergency numberWebbα-Actinin 属于细胞骨架蛋白的血影蛋白家族。 它最早被确认为肌动蛋白交联蛋白，在每个单体的氨基末端与肌动蛋白结合头形成反向平行同型二聚体。 α-actinin 可以与大量参与 … dutch embassy in the united statesWebbAntibody 1A4 (DAKO) recognizes SM a-actin and was used to detect SMCs, whereas antibody HAM56 (DAKO) was used to recognize macrophages in the sections. Activin was detected with monoclonal antibody E4 (Serotec), and follistatin with an anti-peptide antibody (provided by Prof S. Werner, ETH, Zurich, Swit-zerland). dutch embassy london renew passportWebb24 juni 2024 · Definition / general. Actin is a 43000 kDa ubiquitous protein found in all cells. Actins are involved in cell motility (alpha, smooth muscle) and the maintenance of the cytoskeleton (beta and gamma, all cells) … imea trainingWebbimmunocytochemical analysis using antibodies specific for either SM a-actin (Skalli et al., 1986) or SM myosin heavy chain (Kawamoto and Adelstein, 1987). Microscopic evaluation of a number of fields failed to uncover SM a-actin- or SM myosin heavy chain-negative cells (data not shown). Additionally, the expression of SM a-actin in dutch emergency pack lspdfr