Homology bias
Web8 apr. 2024 · This ubiquitin-dependent signaling bias arises through the modification of lysine333 (K333) on the cytoplasmic face of transmembrane helix V. Compared with the GCGR-WT, the mutant GCGR-K333R has impaired ubiquitination, diminished G protein coupling and protein kinase A signaling, but unimpaired potentiation of glucose … Web6 feb. 2015 · Since there are some sequences from the benchmark dataset that shared high sequence identity with the independent dataset PDB186, the tool CD-HIT was applied to remove the sequences from the benchmark dataset having more than 25% sequence identity to any one in a same subset in the independent dataset PDB186 to avoid …
Homology bias
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Web21 nov. 2024 · Since homology variance will affect the experimental results, this study requires homology variance test on the collected sample data. Since Harman’s one-factor test method is a classic method for testing whether the homology variance problem is serious, this method is also adopted in this study. Web26 nov. 2024 · In general, a lower threshold of sequence identity might help reduce the bias due to sequence homology, and in principle, a more reliable training model could be obtained, but the size of the dataset should also be considered ( Wang et al., 2024 ).
Web21 jun. 2016 · If Mek1 kinase plays the same role as in wild-type cells, the default option for programmed DSB repair is homologous bias, which uses homologous chromatids for recombination. When cells undergo defects in the SEI-to-dHJ transition, some of the SEIs may be converted into IH-NCO products, while SEI is stably converted into an IH-CO … Web18 aug. 2006 · The former would limit the prediction power while the latter could not avoid homology bias and overestimate the true success rate. In this study, we constructed a more extensive and meanwhile much more stringent dataset, which covers 12 subcellular locations and in which none of proteins has ⩾25% sequence identity to any others in a …
Web29 apr. 2024 · The overwhelming majority of gene pairs (an average of 86.7%) in B. napus maintained their expression pattern in two diploid progenitors, and approximately 78.1% … Web1 nov. 2002 · Congruence between the sexes in preexisting receiver responses Congruence between the sexes in preexisting receiver responses Alexandra L. Basolo 2002-11-01 00:00:00 Behavioral Ecology Vol. 13 No. 6: 832837 Alexandra L. Basolo School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, NE 68588-0118, USA Preexisting …
WebSubstitution bias, rapid saturation, and the use of mtDNA for nematode systematics Only relatively recently have researchers turned to molecular methods for nematode …
Web6 aug. 2024 · Homoeolog expression bias in resynthesized allotetraploid B. napus. The relative expression levels of the homoeologs are modeled by the size of the circles in the … high cognitive functionWeb23 jun. 2024 · homology在生物学上被翻译成“同源性”,是指在不同生物类群中,由于共同的祖先,在一对结构或基因间表现出来的相似性。 在基因序列(DNA,RNA or Protein)上体 … high cogging torqueWeb19 nov. 2024 · None of the proteins included in dataset S has a pairwise sequence identity of >25% with respect to any other in the same subcellular location. This dataset S is much more rigorous in excluding homology bias and redundancy. Moreover, this dataset is well documented and has been used in benchmarking various predictors [7, 9, 23–30]. 2.2. highcogWebDefinition. Homology modeling or comparative modeling is the prediction of the tertiary structure of an unknown protein using a known three‐dimensional (3D) structure of a … how far is woodbury njWeb15 sep. 2024 · University of Delhi, New Delhi-India. Jan 2024 - Present4 years 4 months. New Delhi Area, India. Currently working as a Ph.D. research scholar at DR.BR Ambedkar Center for Biomedical Research (ACBR-DU) under the supervision of Prof. Daman Saluja. With Senior Research Fellowship (SRF) support from DBT-Indo-Canadian research project. how far is woodland hills from meWeb25 jan. 2024 · To reduce the redundancy of data and avoid the influence of homology bias ( Zou et al., 2024 ), we utilized CD-HIT ( Fu et al., 2012) with a 30% sequence identity cut-off and obtained 911 protein chains. high cohen\u0027s dWeb28 okt. 2006 · Also, the data set used to train PSORT-B contains many proteins with high degrees of sequence identity in a same location group and, hence, may bear a strong homology bias. To overcome these problems, a new … how far is woodland hills from lax