Cytofectin
WebJan 31, 2024 · ANGPTL3の発現を阻害するための二本鎖リボ核酸（dsRNA）であって、前記dsRNAが、センス鎖及びアンチセンス鎖を含み、前記アンチセンス鎖が、表2、3、7、8、9及び10に列挙されるアンチセンス配列のいずれか1つと3つ以下のヌクレオチドが異なる少なくとも15連続ヌクレオチドを含む相補性の領域を ... WebSep 28, 2008 · Cationic amphiphiles (cytofectins) are widely used for the transfection of cultured cells, and may become useful for the development of genetic medicines.
Cytofectin
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Webproved cytofectin, termed GS 2888, which overcomes many of the shortcomings of Lipofectin for delivering ODNs and plasmids to cells. The GS 2888 cytofectin efficiently transfects ODNs and plasmids into many cell types in the presence or absence of serum in the medium, uses a 4- to 10-fold lower concentration of the agent as compared to ... WebSep 17, 1996 · A cytofectin composition comprising an amine having bonded to an attached carbon chain at least a pair of same or different lipoyl moieties selected from a group consisting of an alkyl, alkenyl, alkynyl, alkanoyl, alkenoyl, or alkynoyl groups and at least two hydroxylated, ether containing, or acyloxy containing alkyl, alkenyl, or alkynyl …
WebCytofectin™ - Efficient Transfection of Antisense Oligonucleotides To improve oligonucleotide delivery, researchers at Gilead Sciences developed the Cytofectin™ GS … WebAlthough optimal for the transfection of antisense oligonucleotides, Cytofectin GSV has also been found to be suitable for plasmid transfection. In December 1998, Gilead's antisense technology, including the patents covering the C-5 Propynes and Cytofectin GSV, was purchased by Isis Pharmaceuticals, Inc.
WebAbstract. Cationic lipids (cytofectins) have gained widespread acceptance as pharmaceutical polynucleotide delivery agents for both cultured cell and in vivo … WebGenerally related is a cytofectin:polynucleotide complex that comprises a polynucleotide; a quaternized amine having bonded to an attached carbon chain at least a pair of same or …
WebApr 1, 1996 · This lipid formulation, termed GS 2888 cytofectin, (i) efficiently transfects ODNs and plasmids into many cell types in the presence or absence of 10% serum in …
Webcytofectin, (i) efficiently transfects ODNs and plasmids into many cell types in the presence or absence of 10% serum in the medium, (ii) uses a 4- to 10-fold lower concentration of … imco green frogWebCytofectin Amine Head Group Modification and Degree of Liposome Pegylation: Factors Influencing Gene Transfer The effectiveness of liposome-mediated gene transfer methods hinges, in part, on the nature of the interaction between the DNA cargo and the liposomes. imc of meridianWebThe transfection activity of cytofectin formulations depends greatly on the cationic lipid chemical species, on the presence of particular neutral co-lipids in the formulation, on the … list of knowledge adventureWebProvided is a collection of cytofectins (cytofectins are defined as chemical species that are cationic transfection amphiphiles) or cationic lipids that bind and transport polynucleotides,... imco holdingsWebCROSS REFERENCE TO RELATED APPLICATIONS. This application is a divisional application of U.S. application Ser. No. 11/781,153 filed Jul. 20, 2007, now pending; which claims the be imc of itiWebAug 1, 1996 · To prepare the cytofectin/ON complexes for transfection in one well of a 6-well tissue culture plate, the ON was first diluted into 100 µl pre-warmed Opti-MEM (Gibco BRL) in polystyrene plastic. Similarly, the cytofectin was diluted in another container ( 5 ). imco highlightsGS3815 cytofectin (Glen Research, Sterling, VA) is a formulation of two equivalents of a cationic lipid (dimyristylamidoglycyl- N -α-isopropoxycarbonyl-arginine dihydrochloride, GS3815) with one equivalent of the zwitterion l -α-dioleoylphosphatidylethanolamine (DOPE, Avanti Polar Lipids). list of knock knock jokes for kids