Only certain statin medications interact negatively with grapefruit. This is an issue only for lovastatin (Mevacor) and simvastatin (Zocor, or Vytorin) and typically is only problematic at the highest dosages. Alternative statins like rosuvastatin (Crestor), pravastatin (Pravachol), pitavastatin (Livalo) or fluvastatin (Lescol) … See more The introduction of statin medications has helped patients: 1. Lower LDL (Low-density lipoprotein cholesterol or “bad” cholesterol). 2. … See more Grapefruit contains a chemical that can interfere with your body’s ability to break down or metabolize certain statin medications. When statin takers eat large amounts of … See more WebApr 1, 2024 · Tell your doctor if you regularly drink grapefruit juice. Drinking large amounts of grapefruit juice (more than 1 quart each day) while taking this medicine may increase your risk of muscle injury and could result in kidney problems. Do not drink large amounts of alcohol with this medicine. This could cause unwanted effects on the liver.
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WebFor example, if you drink a lot of grapefruit juice while taking certain statin drugs to lower cholesterol, too much of the drug may stay in your body, increasing your risk for liver and muscle damage that can lead to kidney failure. Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. WebFeb 22, 2024 · Most grapefruit is yellow when ripe and can be 4-6 inches in diameter. The inner flesh tends to be very juicy and pale yellow in color, but there are more recently developed varieties that have dark pink or red pulp. At 9.3 million tonnes produced annually, the grapefruit is behind only the orange and lemon in terms of quantity of citrus fruit. importance of good manners
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WebNov 4, 2024 · Official answer. You should not drink grapefruit juice with simvastatin because it can significantly increase blood levels of simvastatin and increase the risk of … WebDec 11, 2024 · Official answer by Drugs.com Limes, pomegranates, pomelos, and Seville oranges can also interact with some medications, including statins such as atorvastatin. There just hasn't been as much research published regarding how other types of citrus (apart from grapefruit) interact with statins. WebJul 28, 2024 · Doctors warn against consuming Grapefruit juice if you take certain types of medication, such as statins, which are metabolized by the CYP3A4 enzyme. Grapefruit juice inhibits this enzyme so the liver produces less of it, and this affects the action of those drugs – they will be less effective. This is known as a drug interaction. literally going